5-lipoxygenáza leukotrién A syntáza leukotrién A4 syntetáza LTA4 syntáza
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5-Lipoxygenase
Scope note in English
An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes.
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