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1-metyl-4-fenylpyridínium

  1. Subject h.1-metyl-4-fenylpyridínium
    Subject h.1-Methyl-4-phenylpyridinium
    Entry termscyperquat
    English X referencesCyperquat
    Scope note in EnglishAn active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.
    Pharmacology effect herbicídy
    Pharmacology effect Herbicides
    See also reference (FX) in Slovak otrava MPTP
    See also reference (FX) in English MPTP Poisoning
    Links (1) - MeSH descriptor
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Number of the records: 1  

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