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Janus kinázy

  1. Subject h.Janus kinázy
    Subject h.Janus Kinases
    Entry termsJanus kináza
    JAK kinázy
    English X referencesJanus Kinase
    Scope note in EnglishA family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains.
    See also reference (FX) in Slovak domény src, homológne
    See also reference (FX) in English src Homology Domains
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