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angiotenzinogén

  1. Record numberd000808
    Date06.06.2025
    TypeM - MESH
    Topical termangiotenzinogén
    Other termEnglish (Pseudonym) Hypertensinogen
    English (Pseudonym) Renin-Substrate
    English (Pseudonym) SERPINA8
    Slovak (Pseudonym) hypertenzinogén
    Slovak (Pseudonym) proangiotenzín
    Slovak (Pseudonym) substrát renínu
    Slovak (Pseudonym) substrát renínový
    Slovak (Pseudonym) serpín A8
    Slovak (Pseudonym) tetradekapeptid substrátu renínu
    Slovak (Pseudonym) tetradekapeptid renínového substrátu
    Slovak (Pseudonym) SERPINA8
    See also(Skutočné meno) inhibítory serínových proteináz
    UDCD12.644.456.073.070D12.644.861.020D12.776.811.070D12.776.872.020
    NoteAn alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver in response to lowered blood pressure and secreted into blood circulation. Angiotensinogen is the inactive precursor of the ANGIOTENSINS produced in the body by successive enzyme cleavages. Cleavage of angiotensinogen by RENIN yields the decapeptide ANGIOTENSIN I. Further cleavage of angiotensin I (by ANGIOTENSIN CONVERTING ENZYME) yields the potent vasoconstrictor octapeptide ANGIOTENSIN II; and then, via other enzymes, other angiotensins also involved in the hemodynamic-regulating RENIN-ANGIOTENSIN SYSTEM.
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