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buprenorfín

  1. Record numberd002047
    Date06.06.2025
    TypeM - MESH
    Topical termbuprenorfín
    See also(Skutočné meno) analgetiká opioidné
    (Skutočné meno) antagonisty narkotík
    (Skutočné meno) narkotiká
    (Skutočné meno) liečba opioidmi, substitučná
    (Later heading) liečba opioidmi, substitučná
    UDCD03.132.577.249.150D03.605.497.150D03.633.400.686.150D04.615.723.795.150
    NoteA derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
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