Number of the records: 1  

glykozidy srdcové

  1. Record numberd002301
    Date06.06.2025
    TypeM
    Topical termglykozidy srdcové
    Other termEnglish (Pseudonym) Cardiac Glycoside
    English (Pseudonym) Cardiotonic Steroid
    English (Pseudonym) Cardiotonic Steroids
    Slovak (Pseudonym) glykozid srdcový
    Slovak (Pseudonym) steroidy kardiotonické
    Slovak (Pseudonym) steroid kardiotonický
    See also(Skutočné meno) antiarytmiká
    (Skutočné meno) kardiotoniká
    (Skutočné meno) inhibítory enzýmov
    UDCD04.210.500.155.580D09.408.180
    NoteCyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
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