Number of the records: 1

amplifikácia génová

Record number	d005784
Date	06.06.2025
Type	M - MESH
Topical term	amplifikácia génová
Other term	Slovak (Pseudonym) amplifikácia génov
See also	(Skutočné meno) dávka génová
UDC	G05.308.250G05.365.590.310G05.558.315
Note	A selective increase in the number of copies of a gene coding for a specific protein without a proportional increase in other genes. It occurs naturally via the excision of a copy of the repeating sequence from the chromosome and its extrachromosomal replication in a plasmid, or via the production of an RNA transcript of the entire repeating sequence of ribosomal RNA followed by the reverse transcription of the molecule to produce an additional copy of the original DNA sequence. Laboratory techniques have been introduced for inducing disproportional replication by unequal crossing over, uptake of DNA from lysed cells, or generation of extrachromosomal sequences from rolling circle replication.

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Number of the records: 1