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monoaminooxidáza

  1. Record numberd008995
    Date06.06.2025
    TypeM
    Topical termmonoaminooxidáza
    Other termEnglish (Pseudonym) Amine Oxidase (Flavin-Containing)
    English (Pseudonym) MAO
    Slovak (Pseudonym) MAO
    Slovak (Pseudonym) aminooxidáza (obsahujúca flavín)
    UDCD08.811.682.664.750
    NoteAn enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4.
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