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rifampicín
Record number d012293 Date 06.06.2025 Type M Topical term rifampicín Other term English (Pseudonym) Rifampicin
See also (Skutočné meno) antibiotiká antituberkulózne
(Skutočné meno) antileprotiká
(Skutočné meno) inhibítory syntézy nukleových kyselín
(Skutočné meno) induktory cytochrómu P-450 CYP2B6
(Skutočné meno) induktory cytochrómu P-450 CYP2C8
(Skutočné meno) induktory cytochrómu P-450 CYP2C19
(Skutočné meno) induktory cytochrómu P-450 CYP2C9
(Skutočné meno) induktory cytochrómu P-450 CYP3A
UDC D03.633.400.811.700D04.345.295.750.700 Note A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160) 
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Number of the records: 1