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Lambertov-Eatonov myastenický syndróm
Record number d015624 Date 06.06.2025 Type M - MESH Topical term Lambertov-Eatonov myastenický syndróm Other term English (Pseudonym) Eaton-Lambert Syndrome
English (Pseudonym) Myasthenic Syndrome, Lambert-Eaton
Slovak (Pseudonym) syndróm myastenický
Slovak (Pseudonym) Eatonov-Lambertov syndróm
UDC C04.588.614.550.500.225C04.730.856.490.225C10.114.656.150C10.574.781.588.225C10.668.758.725.150C20.111.258.500.150 Note An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471) 
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