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komplex komplementu atakujúci membrány
Record number d015938 Date 06.06.2025 Type M Topical term komplex komplementu atakujúci membrány Other term English (Pseudonym) Complement Complex C5b-9
English (Pseudonym) Membrane Attack Complex
Slovak (Pseudonym) MAC
Slovak (Pseudonym) membrány atakujúci komplex
Slovak (Pseudonym) C5b-9
See also (Later heading) cytotoxicita imunologická
(Skutočné meno) faktory imunologické
UDC D12.776.124.486.274.930 Note A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the membrane attack complex or MAC. 
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