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lupus antikoagulans

  1. Record numberd016682
    Date06.06.2025
    TypeM
    Topical termlupus antikoagulans
    Other termEnglish (Pseudonym) Lupus Anticoagulant
    English (Pseudonym) Lupus Anticoagulant Autoantibodies
    English (Pseudonym) Lupus Anticoagulant Autoantibody
    Slovak (Pseudonym) inhibítor koagulácie, lupusový
    Slovak (Pseudonym) antikoagulant lupusový
    Slovak (Pseudonym) autoprotilátky lupusové antikoagulačné
    Slovak (Pseudonym) autoprotilátka antikoagulačná lupusová
    See also(Later heading) lupus erythematosus, systémový
    (Skutočné meno) faktory imunologické
    (Skutočné meno) syndróm antifosfolipidový
    UDCD12.776.124.486.485.114.323.210.600D12.776.124.790.651.114.323.210.600D12.776.377.715.548.114.323.210.600D23.113.475
    NoteAn antiphospholipid antibody found in association with a variety of diseases (e.g., SYSTEMIC LUPUS ERYTHEMATOSUS and ANTIPHOSPHOLIPID SYNDROME) as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.
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