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motívy helix-otáčka-helix

  1. Record numberd019077
    Date06.06.2025
    TypeM - MESH
    Topical termmotívy helix-otáčka-helix
    Other termEnglish (Pseudonym) HTH Motifs
    Slovak (Pseudonym) motívy helix-turn-helix
    Slovak (Pseudonym) HTH motívy
    See also(Later heading) proteíny viažuce DNA
    UDCG02.111.570.820.709.275.500.360.360
    NoteThe first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the turn. The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9)
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