Number of the records: 1
receptory pre-B-buniek
Record number d054420 Date 06.06.2025 Type M - MESH Topical term receptory pre-B-buniek Other term Slovak (Pseudonym) receptory pre-B buniek
UDC D12.776.124.790.651.950.750D12.776.377.715.548.950.750D12.776.543.750.705.816.821.750 Note Membrane proteins in precursor B-LYMPHOCYTES (pre-B Cells). They are composed of membrane-bound MU IMMUNOGLOBULIN HEAVY CHAINS in complex with SURROGATE LIGHT CHAINS instead of conventional IMMUNOGLOBULIN LIGHT CHAINS. Only successful rearrangement of the VDJ segments, at the Ig heavy chain gene locus (IMMUNOGLOBULIN HEAVY CHAIN GENES), will generate mu heavy chains that can pair with surrogate light chains. Thus formation of the pre-B cell receptors is an important checkpoint in the development of mature B cells. subject heading
Number of the records: 1