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denaturácia nukleových kyselín

  1. Subject h.denaturácia nukleových kyselín
    Subject h.Nucleic Acid Denaturation
    Entry termsdenaturácia DNA
    topenie DNA
    denaturácia RNA
    English X referencesDNA Denaturation
    DNA Melting
    RNA Denaturation
    Scope note in EnglishDisruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.
    See also reference (FX) in Slovak stabilita RNA
    See also reference (FX) in English RNA Stability
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    (2) - MeSH descriptor
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