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transdukcia signálna

  1. Subject h.transdukcia signálna
    Subject h.Signal Transduction
    Entry termssignalizácia bunková
    receptorom sprostredkovaný prenos signálu
    receptormi sprostredkovaná signálna transdukcia
    dráhy signálne
    prenos signálov
    dráhy signálneho prenosu
    dráhy signálnej transdukcie
    systémy signálneho prenosu
    systémy signálnej transdukcie
    English X referencesCell Signaling
    Receptor-Mediated Signal Transduction
    Signal Pathways
    Scope note in EnglishThe intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
    See also reference (FX) in Slovak kanály iónové
    See also reference (FX) in English Ion Channels
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    (6) - MeSH descriptor
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