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simvastatín

  1. Subject h.simvastatín
    Subject h.Simvastatin
    Scope note in EnglishA derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.
    Pharmacology effect anticholesterolemiká
    inhibítory hydroxymetylglutaryl-CoA-reduktázy
    hypolipidemiká
    Pharmacology effect Anticholesteremic Agents
    Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Hypolipidemic Agents
    See also reference (FX) in Slovak rosuvastatín kalcium
    See also reference (FX) in English Rosuvastatin Calcium
    Links (45) - ARTICLES
    (1) - MeSH descriptor
    (2) - CiBaMed
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