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chiméra zameraná na proteolýzu

Subject h.	chiméra zameraná na proteolýzu
Subject h.	Proteolysis Targeting Chimera
Entry terms	chiméra proteolytická zlúčeniny na báze cereblonu, malomolekulárne PROTACs na báze IAP PROTACs na báze MDM2 proteínu PROTACs PROTACs fosfo-dependentné fospfoPROTACs PROTACs na báze VHL PROTAC chiméra zameraná na proteolýzu chiméry cielené na proteolýzu chiméry zamerané na proteolýzu
English X references	Cereblon-Based Small-Molecule Compounds IAP-Based PROTACs MDM2 Protein-Based PROTACs PROTAC Proteolysis Targeting Chimera PROTACs Phospho-Dependent PROTACs PhosphoPROTACs Proteolysis Targeting Chimeras VHL-Based PROTACs
Scope note in English	Bifunctional molecules that are designed to recruit E3 UBIQUITIN LIGASE to a specific target protein. Proteolysis targeting chimera consist of a target protein ligand connected via a linker to an E3 ligand. They promote association of E3 with specific target proteins tagged for degradation via the PROTEASOME.

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Number of the records: 1