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F-box-WD repetície obsahujúci proteín 7
Record number d000073979 Date 06.06.2025 Type M - MESH Topical term F-box-WD repetície obsahujúci proteín 7 Other term Slovak (Pseudonym) F-box a WD-40 doménu-obsahujúci proteín
Slovak (Pseudonym) FBXW7 proteín
UDC D08.811.464.938.750.750.750D12.776.157.169.750D12.776.167.242 Note A component of SCF(FBW7) UBIQUITIN LIGASE that contains an F-box motif and multiple WD REPEATS. It recognizes and binds phosphorylated signals in several proteins involved in CELL PROLIFERATION and targets them to the SCF complex for UBIQUITINATION. Targets include CYCLIN E; PROTO-ONCOGENE PROTEINS C-JUN; PROTO-ONCOGENE PROTEINS C-MYC; and JNK MITOGEN-ACTIVATED PROTEIN KINASES. 
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Number of the records: 1