Number of the records: 1  

simvastatín

  1. Record numberd019821
    Date06.06.2025
    TypeM
    Topical termsimvastatín
    See also(Skutočné meno) anticholesterolemiká
    (Skutočné meno) hypolipidemiká
    (Skutočné meno) inhibítory hydroxymetylglutaryl-CoA-reduktázy
    (Skutočné meno) rosuvastatín kalcium
    (Later heading) rosuvastatín kalcium
    UDCD02.455.426.559.847.638.400.900D04.615.638.400.900
    NoteA derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.
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Number of the records: 1  

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