Number of the records: 1  

presenilín-1

  1. Record numberd053764
    Date06.06.2025
    TypeM - MESH
    Topical termpresenilín-1
    UDCD12.776.543.696.500
    NoteIntegral membrane protein of Golgi and endoplasmic reticulum. Its homodimer is an essential component of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. PSEN1 mutations cause early-onset ALZHEIMER DISEASE type 3 that may occur as early as 30 years of age in humans.
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Number of the records: 1  

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