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  1. 1.prednimustín

    Subject h.prednimustín
    Subject h.Prednimustine
    Scope note in EnglishEster of CHLORAMBUCIL and PREDNISOLONE used as a combination alkylating agent and synthetic steroid to treat various leukemias and other neoplasms. It causes gastrointestinal and bone marrow toxicity.
    Pharmacology effect antineoplastiká alkylačné
    Pharmacology effect Antineoplastic Agents, Alkylating
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  2. 2.semustín

    Subject h.semustín
    Subject h.Semustine
    Entry termsmetyl-CCNU
    English X referencesMethyl-CCNU
    Scope note in English4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
    Pharmacology effect antineoplastiká alkylačné
    Pharmacology effect Antineoplastic Agents, Alkylating
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  3. 3.altretamín

    Subject h.altretamín
    Subject h.Altretamine
    Entry termsHEMEL
    hexametylmelamín
    HMM
    English X referencesHemel
    Hexamethylmelamine
    Scope note in EnglishA hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.
    Pharmacology effect antineoplastiká alkylačné
    Pharmacology effect Antineoplastic Agents, Alkylating
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  4. 4.horčica anilínová

    Subject h.horčica anilínová
    Subject h.Aniline Mustard
    Entry termsN,N-bis(2-chloroetyl)anilín
    Scope note in EnglishAlkylating anti-neoplastic agent.
    Pharmacology effect antineoplastiká alkylačné
    Pharmacology effect Antineoplastic Agents, Alkylating
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  5. 5.mitolaktol

    Subject h.mitolaktol
    Subject h.Mitolactol
    Entry termsdibrómdulcitol
    dibrómdulcit
    English X referencesDibromodulcitol
    Scope note in EnglishAlkylating antineoplastic toxic to bone marrow; used in breast cancer, also in combination with other drugs.
    Pharmacology effect antineoplastiká alkylačné
    Pharmacology effect Antineoplastic Agents, Alkylating
    Links (1) - ARTICLES
    (1) - BOOKS
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  6. 6.zlúčeniny horčičného dusíka

    Subject h.zlúčeniny horčičného dusíka
    Subject h.Nitrogen Mustard Compounds
    Entry termsyperity dusíkaté
    ICR 170
    Scope note in EnglishA group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens.
    Pharmacology effect antineoplastiká alkylačné
    Pharmacology effect Antineoplastic Agents, Alkylating
    Links (1) - ARTICLES
    (1) - CiBaMed
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  7. 7.karmustín

    Subject h.karmustín
    Subject h.Carmustine
    English X referencesBCNU
    Scope note in EnglishA cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
    Pharmacology effect antineoplastiká alkylačné
    Pharmacology effect Antineoplastic Agents, Alkylating
    Links (1) - ARTICLES
    (1) - BOOKS
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  8. 8.melfalan

    Subject h.melfalan
    Subject h.Melphalan
    Entry termsmedfalan
    merfalan
    fenylalanínmustard
    sarkolyzín
    English X referencesMedphalan
    Merphalan
    Phenylalanine Mustard
    Sarcolysine
    Sarkolysin
    Scope note in EnglishAn alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen.
    Pharmacology effect antineoplastiká alkylačné
    agonisty myeloablácie
    Pharmacology effect Antineoplastic Agents, Alkylating
    Myeloablative Agonists
    Links (19) - ARTICLES
    (1) - CiBaMed
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  9. 9.etylmetánsulfonát

    Subject h.etylmetánsulfonát
    Subject h.Ethyl Methanesulfonate
    English X referencesEthylmethane Sulfonate
    Scope note in EnglishAn antineoplastic agent with alkylating properties. It also acts as a mutagen by damaging DNA and is used experimentally for that effect.
    Pharmacology effect antineoplastiká alkylačné
    mutagény
    Pharmacology effect Antineoplastic Agents, Alkylating
    Mutagens
    Links (3) - ARTICLES
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  10. 10.dakarbazín

    Subject h.dakarbazín
    Subject h.Dacarbazine
    English X referencesDTIC
    Scope note in EnglishAn antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564)
    Pharmacology effect antineoplastiká alkylačné
    Pharmacology effect Antineoplastic Agents, Alkylating
    Links (6) - ARTICLES
    (1) - CiBaMed
    (2) - BOOKS
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