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Records found: 3  
Your query: Author Sysno/Doc.kind = "^sllk_un_auth d012608 250m^"
  1. Subject h.proteíny PrPSc
    Subject h.PrPSc Proteins
    English X referencesScrapie Agent
    Scrapie PrP
    Scope note in EnglishAbnormal isoform of PRION PROTEINS resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES).
    Links (5) - ARTICLES
    (1) - MeSH descriptor
    (1) - CiBaMed
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  2. Subject h.prionózy
    Subject h.Prion Diseases
    Entry termschoroby priónové
    encefalopatie spongiformné prenosné
    encefalopatie spongioformné prenosné
    encefalopatie špongioformné prenosné
    demencie prenosné
    English X referencesDementias, Transmissible
    Spongiform Encephalopathies, Transmissible
    Transmissible Dementias
    Scope note in EnglishA group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)
    Links (58) - ARTICLES
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    (15) - CiBaMed
    (1) - ELECTRONIC RESOURCES
    (11) - BOOKS
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  3. Subject h.prióny
    Subject h.Prions
    Entry termsprión
    vírus encefalopatie noriek
    English X referencesMink Encephalopathy Virus
    Prion
    Scope note in EnglishSmall proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.
    Links (39) - ARTICLES
    (1) - MeSH descriptor
    (16) - CiBaMed
    (10) - BOOKS
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