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systém enzýmov cytochrómu P-450
Č. záznamu d003577 Dátum 06.06.2025 Typ M - MESH Tematický termín systém enzýmov cytochrómu P-450 Iný termín Angličtina (Pseudonym) Cytochrome P-450
Angličtina (Pseudonym) Cytochrome P-450-Dependent Monooxygenase
Angličtina (Pseudonym) Cytochrome P-450 Enzyme
Angličtina (Pseudonym) P-450 Enzyme
Angličtina (Pseudonym) P450 Enzyme
Slovenčina (Pseudonym) rodina CYP450
Slovenčina (Pseudonym) superrodina CYP450
Slovenčina (Pseudonym) systém cytochrómu P-450, enzýmový
Slovenčina (Pseudonym) CYP450 rodina enzýmov
Slovenčina (Pseudonym) cytochróm P-450
Slovenčina (Pseudonym) enzým cytochróm P450
Slovenčina (Pseudonym) enzýmy cytochróm P450
Slovenčina (Pseudonym) rodiny cytochrómov P450
Slovenčina (Pseudonym) cytochróm P 450 monooxygenáza
Slovenčina (Pseudonym) cytochróm P450 oxygenáza
Slovenčina (Pseudonym) monooxygenázy závislé od cytochrómu P-450
Slovenčina (Pseudonym) superrodina cytochrómov P450
Slovenčina (Pseudonym) P450 enzým
Slovenčina (Pseudonym) P-450 enzýmy
MDT D08.244.453D08.811.682.690.708.170D12.776.422.220.453 Poznámka A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. 
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