Počet záznamov: 1
receptory pre LDL
Č. záznamu d011973 Dátum 06.06.2025 Typ M Tematický termín receptory pre LDL Iný termín Angličtina (Pseudonym) LDL Receptors
Angličtina (Pseudonym) Lipoprotein LDL Receptors
Angličtina (Pseudonym) Receptors, Low Density Lipoprotein
Slovenčina (Pseudonym) receptory LDL
Slovenčina (Pseudonym) receptory lipoproteínov LDL
Slovenčina (Pseudonym) receptory pre lipoproteíny LDL
Slovenčina (Pseudonym) receptory pre nízkodenzitné lipoproteíny
Slovenčina (Pseudonym) receptory pre lipoproteíny s nízkou hustotou
Pozri tiež (Novšie záhlavie) lipoproteíny, LDL
(Skutočné meno) lipoproteíny, LDL
(Novšie záhlavie) hypercholesterolémia homozygotná familiárna
MDT D12.776.543.750.710.450 Poznámka Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking. 
predmetové heslo
Počet záznamov: 1