Počet záznamov: 1
zidovudín
Č. záznamu d015215 Dátum 12.05.2026 Typ M - MESH Tematický termín zidovudín Iný termín Angličtina (Pseudonym) Azidothymidine
Angličtina (Pseudonym) AZT (Antiviral)
Angličtina (Pseudonym) Azidothymidine
Angličtina (Pseudonym) AZT (Antiviral)
Angličtina (Pseudonym) 3'-Azido-2',3'-Dideoxythymidine
Angličtina (Pseudonym) 3'-Azido-3'-deoxythymidine
Angličtina (Pseudonym) AZT Antiviral
Angličtina (Pseudonym) AZT, Antiviral
Slovenčina (Pseudonym) azidotymidín
Slovenčina (Pseudonym) AZT (antivírusový)
Slovenčina (Pseudonym) AZT, antivirotikum
Slovenčina (Pseudonym) 3'-azido-2',3'-dideoxytimidín
Slovenčina (Pseudonym) 3'-azido-3'-deoxytimidín
Slovenčina (Pseudonym) BW A509U
Slovenčina (Pseudonym) BWA-509U
Slovenčina (Pseudonym) Retrovir
Pozri tiež (Skutočné meno) antimetabolity
(Skutočné meno) inhibítory reverznej transkriptázy
(Skutočné meno) látky proti HIV
MDT D03.383.742.680.705.950D13.570.230.500.950D13.570.230.855.950D13.570.685.705.950 Poznámka A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia. 
predmetové heslo
Počet záznamov: 1