Počet záznamov: 1
komplex podporujúci anafázu - cyklozóm
Heslo komplex podporujúci anafázu - cyklozóm Heslo anglicky Anaphase-Promoting Complex-Cyclosome Odkazy anafázu podporujúci komplex - cyklozóm Vysvetľujúca pozn. v angl. An E3 ubiquitin ligase primarily involved in regulation of the metaphase-to-anaphase transition during MITOSIS through ubiquitination of specific CELL CYCLE PROTEINS. Enzyme activity is tightly regulated through subunits and cofactors, which modulate activation, inhibition, and substrate specificity. The anaphase-promoting complex, or APC-C, is also involved in tissue differentiation in the PLACENTA, CRYSTALLINE LENS, and SKELETAL MUSCLE, and in regulation of postmitotic NEURONAL PLASTICITY and excitability. 
predmetové heslo
Počet záznamov: 1