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myši knokautované
SYS d018345 LBL 00000nz--a2200000o--4500 005 20250606214824.3 008 930603|||anznnbabn-----------|-a|a------ 040 $b slo $a DNLM $d BA006 065 $a B01.050.050.136.500.500 065 $a B01.050.150.900.649.313.992.635.505.500.550.455 065 $a B01.050.150.900.649.313.992.635.505.500.800.500 066 $a 01 $c 03 150 $a myši knokautované $x AB $x AH $x BL $x CF $x CL $x EM $x GD $x GE $x IM $x IN $x ME $x MI $x PH $x PS $x PX $x SU $x UR $x VI $2 slo 450 $w v $a Knockout Mice $2 eng 450 $w v $a myši knockout $2 slo 550 $7 sllk_us_auth*d005818 $Y Genetic Engineering $w b $a inžinierstvo genetické 550 $7 sllk_us_auth*d055786 $Y Gene Knockout Techniques $w p $a techniky inaktivácie génu 550 $7 sllk_us_auth*d055786 $Y Gene Knockout Techniques $w b $a techniky inaktivácie génu 665 $a 94 $2 eng 665 $a Mice (1992-1993) $2 eng 680 9-
$i Strains of mice in which certain GENES of their GENOMES have been disrupted, or knocked-out. To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes. $2 eng 680 $a NIM no qualif when exper animal; do not forget also to check MICE $2 eng 750 -2
$a Mice, Knockout $2 eng 980 $x M
Počet záznamov: 1