Effects of frozen storage conditions and freezing rate on the stability of coagulation proteins in human plasma

0013557 2024 RIV US eng J
Fenclová, Tereza - Mareček, František - Hrachovinová, Ingrid^G
Effects of frozen storage conditions and freezing rate on the stability of coagulation proteins in human plasma.
Blood coagulation & fibrinolysis. Vol. 34, no. 6 (2023), s. 377-384. ISSN 0957-5235
Institucionální podpora: RVO:00023736
Klíčová slova: blood coagulation * freezing * plasma
Cite Score: 1.800, rok: 2022; SJR: 0.310, rok: 2022; IF: 1.100, rok: 2022
DOI: 10.1097/MBC.0000000000001239

Anotace: Degradation of coagulation proteins in frozen plasma may influence assay results. The aims of this study were to explore the changes in coagulation parameters in patient plasma and internal quality control (IQC) after different freezing and storage conditions during the short-term and long-term periods. This study is unique in its conception as a practical guide for the handling of frozen plasma samples in modern laboratory settings.