A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
Pharmacology effect
látky bronchodilatačné inhibítory fosfodiesteráz antagonisty purinergných receptorov P1 látky vazodilatačné
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
Pharmacology effect
stimulanciá centrálneho nervového systému inhibítory fosfodiesteráz antagonisty purinergných receptorov P1
Pharmacology effect
Central Nervous System Stimulants Phosphodiesterase Inhibitors Purinergic P1 Receptor Antagonists
A drug combination that contains THEOPHYLLINE and ethylenediamine. It is more soluble in water than theophylline but has similar pharmacologic actions. It's most common use is in bronchial asthma, but it has been investigated for several other applications.
Pharmacology effect
látky bronchodilatačné kardiotoniká inhibítory fosfodiesteráz antagonisty purinergných receptorov P1
