Search results

Records found: 9  
Your query: Author Sysno/Doc.kind = "^sllk_un_auth d019380 250m^"
 In the basket (0)

  1. 1.terapia antiretrovírusová vysoko aktívna

    Subject h.terapia antiretrovírusová vysoko aktívna
    Subject h.Antiretroviral Therapy, Highly Active
    Entry termsHAART
    terapia antiretrovírusová vysoko účinná
    terapia antiretrovírusová vysokoúčinná
    terapia antiretrovírusová kombinovaná
    English X referencesCombination Antiretroviral Therapy
    HAART
    Highly Active Antiretroviral Therapy
    Scope note in EnglishDrug regimens, for patients with HIV INFECTIONS, that aggressively suppress HIV replication. The regimens usually involve administration of three or more different drugs including a protease inhibitor.
    See also reference (FX) in Slovak látky proti HIV
    See also reference (FX) in English Anti-HIV Agents
    Links (37) - ARTICLES
    (2) - MeSH descriptor
    (5) - CiBaMed
    (6) - BOOKS
    subject heading

    subject heading

  2. 2.zidovudín

    Subject h.zidovudín
    Subject h.Zidovudine
    Entry termsazidotymidín
    AZT (antivírusový)
    English X referencesAZT (Antiviral)
    Azidothymidine
    Scope note in EnglishA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.
    Pharmacology effect látky proti HIV
    antimetabolity
    inhibítory reverznej transkriptázy
    Pharmacology effect Anti-HIV Agents
    Antimetabolites
    Reverse Transcriptase Inhibitors
    Links (9) - ARTICLES
    (5) - BOOKS
    subject heading

    subject heading

  3. 3.lamivudín

    Subject h.lamivudín
    Subject h.Lamivudine
    Entry terms2',3'-dideoxy-3'-tiacytidín
    2(1H)-pyrimidinón, 4-amino-1-(2-(hydroxymetyl)-1,3-oxatiolan-5-yl)-, (2R-cis)-
    3TC lamivudín
    BCH-189
    Epivir
    GR-109714X
    GR109714X
    lamivudín, (+)-cis-
    lamivudín, (+-)-trans-
    English X references2',3'-Dideoxy-3'-thiacytidine
    2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-
    3TC Lamivudine
    Lamivudine, (+)-cis-
    Lamivudine, (+-)-trans-
    Scope note in EnglishA reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
    Pharmacology effect látky proti HIV
    inhibítory reverznej transkriptázy
    Pharmacology effect Anti-HIV Agents
    Reverse Transcriptase Inhibitors
    Links (21) - ARTICLES
    (6) - CiBaMed
    (2) - BOOKS
    subject heading

    subject heading

  4. 4.stavudín

    Subject h.stavudín
    Subject h.Stavudine
    Entry terms2',3'-didehydro-3'-deoxytymidín
    d4T
    English X references2',3'-Didehydro-3'-deoxythymidine
    D4T
    Scope note in EnglishA dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
    Pharmacology effect látky proti HIV
    antimetabolity
    inhibítory reverznej transkriptázy
    Pharmacology effect Anti-HIV Agents
    Antimetabolites
    Reverse Transcriptase Inhibitors
    subject heading

    subject heading

  5. 5.delavirdín

    Subject h.delavirdín
    Subject h.Delavirdine
    Scope note in EnglishA potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
    Pharmacology effect látky proti HIV
    inhibítory reverznej transkriptázy
    Pharmacology effect Anti-HIV Agents
    Reverse Transcriptase Inhibitors
    subject heading

    subject heading

  6. 6.trichosantín

    Subject h.trichosantín
    Subject h.Trichosanthin
    Entry termsalfa-trichosantín
    zlúčenina Q
    English X referencesCompound Q
    alpha-Trichosanthin
    Scope note in EnglishPlant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS.
    Pharmacology effect abortíva nesteroidné
    látky proti HIV
    antineoplastiká fytogénne
    Pharmacology effect Abortifacient Agents, Nonsteroidal
    Anti-HIV Agents
    Antineoplastic Agents, Phytogenic
    subject heading

    subject heading

  7. 7.nevirapín

    Subject h.nevirapín
    Subject h.Nevirapine
    Scope note in EnglishA potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
    Pharmacology effect látky proti HIV
    induktory cytochrómu P-450 CYP3A
    inhibítory reverznej transkriptázy
    Pharmacology effect Anti-HIV Agents
    Cytochrome P-450 CYP3A Inducers
    Reverse Transcriptase Inhibitors
    Links (4) - ARTICLES
    subject heading

    subject heading

  8. 8.didanozín

    Subject h.didanozín
    Subject h.Didanosine
    Entry terms2',3'-dideoxyinozín
    dideoxyinozín
    ddI (antivirotikum)
    English X references2',3'-Dideoxyinosine
    Dideoxyinosine
    ddI (Antiviral)
    Scope note in EnglishA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.
    Pharmacology effect látky proti HIV
    antimetabolity
    inhibítory reverznej transkriptázy
    Pharmacology effect Anti-HIV Agents
    Antimetabolites
    Reverse Transcriptase Inhibitors
    Links (1) - BOOKS
    subject heading

    subject heading

  9. 9.zalcitabín

    Subject h.zalcitabín
    Subject h.Zalcitabine
    Entry terms2',3'-dideoxycytidín
    dideoxycytidín
    ddC (antivirotikum)
    English X references2',3'-Dideoxycytidine
    Dideoxycytidine
    ddC (Antiviral)
    Scope note in EnglishA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy.
    Pharmacology effect látky proti HIV
    antimetabolity
    inhibítory reverznej transkriptázy
    Pharmacology effect Anti-HIV Agents
    Antimetabolites
    Reverse Transcriptase Inhibitors
    Links (2) - BOOKS
    subject heading

    subject heading



  This site uses cookies to make them easier to browse. Learn more about how we use cookies.

Accept allSettingsReject all