A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.
Pharmacology effect
látky pôsobiace pozitívne na kostnú denzitu antagonisty estrogénu modulátory estrogénových receptorov, selektívne
Pharmacology effect
Bone Density Conservation Agents Estrogen Antagonists Selective Estrogen Receptor Modulators
A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. Note that ENCLOMIPHENE and ZUCLOMIPHENE are the (E) and (Z) isomers of Clomiphene respectively.
One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
Pharmacology effect
antineoplastiká hormonálne látky pôsobiace pozitívne na kostnú denzitu antagonisty estrogénu modulátory estrogénových receptorov, selektívne
Pharmacology effect
Antineoplastic Agents, Hormonal Bone Density Conservation Agents Estrogen Antagonists Selective Estrogen Receptor Modulators