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SYS d011238 LBL 00000cx--j22000003--45-- 005 20240119201137.0 100 $a 19920530csloy0103----ba0 152 $b mesh 250 $a prednimustín $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 91(80); was see under CHLORAMBUCIL 1980-90 $8 eng 300 1-
$a Chlorambucil (1966-1974) /analogs & derivatives (1975-1979) $8 eng 300 1-
$a Prednisolone (1966-1974) /analogs & derivatives (1975-1979) $8 eng 330 1-
$a Ester of CHLORAMBUCIL and PREDNISOLONE used as a combination alkylating agent and synthetic steroid to treat various leukemias and other neoplasms. It causes gastrointestinal and bone marrow toxicity. $8 eng 550 $3 sllk_un_auth*d018906 $Y Antineoplastic Agents, Alkylating $5 P $a antineoplastiká alkylačné 686 $a D02.455.526.728.650.156.700 686 $a D04.210.500.745.432.769.795.700 750 $a Prednimustine $8 eng 801 -0
$a US $b DNLM $c 19920530 801 -2
$a SK $b BA006 $c 20050729 980 $x M SYS d012673 LBL 00000nx--j22000003--45-- 005 20240119201158.1 100 $a 19921119csloy0103----ba0 152 $b mesh 250 $a semustín $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 91(75); was see under NITROSOUREA COMPOUNDS 1975-90 $8 eng 300 1-
$a Cyclohexanes (1966-1974) $8 eng 300 1-
$a Nitroso Compounds (1966-1972) $8 eng 300 1-
$a Nitrosourea Compounds (1973-1974) $8 eng 300 1-
$a Urea (1966-1972) $8 eng 330 1-
$a 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent. $8 eng 450 $a Methyl-CCNU $5 e $8 eng 450 $a metyl-CCNU $5 e $8 slo 550 $3 sllk_un_auth*d018906 $Y Antineoplastic Agents, Alkylating $5 P $a antineoplastiká alkylačné 686 $a D02.065.950.594.440.700 686 $a D02.654.692.440.700 750 $a Semustine $8 eng 801 -0
$a US $b DNLM $c 19921119 801 -2
$a SK $b BA006 $c 20070706 980 $x M SYS d006585 LBL 00000cx--j22000003--45-- 005 20240119201017.7 100 $a 19921119csloy0103----ba0 152 $b mesh 250 $a altretamín $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 92; was HEXAMETHYLMELAMINE 1975-91 (see under TRIAZINES 1975-90) $8 eng 300 1-
$a Dimethylamines (1973-1974) $8 eng 300 1-
$a Triazines (1970-1974) $8 eng 330 1-
$a A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine. $8 eng 450 $a Hemel $5 e $8 eng 450 $a Hexamethylmelamine $5 e $8 eng 450 $a HEMEL $5 e $8 slo 450 $a hexametylmelamín $5 e $8 slo 450 $a HMM $5 e $8 slo 550 $3 sllk_un_auth*d018906 $Y Antineoplastic Agents, Alkylating $5 P $a antineoplastiká alkylačné 686 $a D03.383.931.135 750 $a Altretamine $8 eng 801 -0
$a US $b DNLM $c 19921119 801 -2
$a SK $b BA006 $c 20031022 980 $x M SYS d000816 LBL 00000cx--j2200000---45-- 005 20240119200836.0 100 $a 19920721asloy0103----ba0 152 $b mesh 250 $a horčica anilínová $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 1991(1976) $8 eng 300 1-
$a Aniline Compounds (1970-1975) $8 eng 300 1-
$a Nitrogen Mustard Compounds (1970-1975) $8 eng 330 1-
$a Alkylating anti-neoplastic agent. $8 eng 450 $a N,N-bis(2-chloroetyl)anilín $5 e $8 slo 550 $3 sllk_un_auth*d018906 $Y Antineoplastic Agents, Alkylating $5 P $a antineoplastiká alkylačné 686 $a D02.455.526.728.650.050 750 $a Aniline Mustard $8 eng 801 -0
$a US $b DNLM $c 19920721 801 -2
$a SK $b BA006 $c 20070706 801 -2
$a SK $b BA006 $c 20141031 980 $x M SYS d008936 LBL 00000cx--j22000003--45-- 005 20240119201057.7 100 $a 19990101csloy0103----ba0 152 $b mesh 250 $a mitolaktol $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 81; was DIBROMODULCITOL 1974-80 $8 eng 300 1-
$a Antineoplastic Agents (1966-1973) $8 eng 300 1-
$a Bromine (1966-1973) $8 eng 330 1-
$a Alkylating antineoplastic toxic to bone marrow; used in breast cancer, also in combination with other drugs. $8 eng 450 $a Dibromodulcitol $5 e $8 eng 450 $a dibrómdulcitol $5 e $8 slo 450 $a dibrómdulcit $5 e $8 slo 550 $3 sllk_un_auth*d018906 $Y Antineoplastic Agents, Alkylating $5 P $a antineoplastiká alkylačné 686 $a D02.033.800.400.500 686 $a D09.853.400.500 750 $a Mitolactol $8 eng 801 -0
$a US $b DNLM $c 19990101 801 -2
$a SK $b BA006 $c 20020704 980 $x M SYS d009588 LBL 00000nx--j22000003--45-- 005 20240119201109.9 100 $a 19990101csloy0103----ba0 152 $b mesh 250 $a zlúčeniny horčičného dusíka $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 330 1-
$a A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens. $8 eng 450 $a yperity dusíkaté $5 e $8 slo 450 $a ICR 170 $5 e $8 slo 550 $3 sllk_un_auth*d018906 $Y Antineoplastic Agents, Alkylating $5 P $a antineoplastiká alkylačné 686 $a D02.455.526.728.650 750 $a Nitrogen Mustard Compounds $8 eng 801 -0
$a US $b DNLM $c 19990101 801 -2
$a SK $b BA006 $c 20001123 820 $a do not confuse with NITROGEN MUSTARD, a specific chemical $8 eng 980 $x M SYS d002330 LBL 00000nx--j22000003--45-- 005 20240119200902.3 100 $a 19990101csloy0103----ba0 152 $b mesh 250 $a karmustín $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 73(72) $8 eng 300 1-
$a Alkylating Agents (1966-1971) $8 eng 300 1-
$a Nitroso Compounds (1966-1971) $8 eng 300 1-
$a Urea (1966-1971) $8 eng 330 1-
$a A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed) $8 eng 450 $a BCNU $5 e $8 eng 550 $3 sllk_un_auth*d018906 $Y Antineoplastic Agents, Alkylating $5 P $a antineoplastiká alkylačné 686 $a D02.065.950.594.247 686 $a D02.654.692.247 750 $a Carmustine $8 eng 801 -0
$a US $b DNLM $c 19990101 801 -2
$a SK $b BA006 $c 20070706 980 $x M SYS d008558 LBL 00000cx--j22000003--45-- 005 20240119201052.2 100 $a 19990101csloy0103----ba0 152 $b mesh 250 $a melfalan $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 330 1-
$a An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen. $8 eng 450 $a Medphalan $5 e $8 eng 450 $a Merphalan $5 e $8 eng 450 $a Phenylalanine Mustard $5 e $8 eng 450 $a Sarcolysine $5 e $8 eng 450 $a Sarkolysin $5 e $8 eng 450 $a medfalan $5 e $8 slo 450 $a merfalan $5 e $8 slo 450 $a fenylalanínmustard $5 e $8 slo 450 $a sarkolyzín $5 e $8 slo 550 $3 sllk_un_auth*d018906 $Y Antineoplastic Agents, Alkylating $5 P $a antineoplastiká alkylačné 550 $3 sllk_un_auth*d019653 $Y Myeloablative Agonists $5 P $a agonisty myeloablácie 686 $a D02.455.526.728.650.594 686 $a D12.125.072.050.685.500 750 $a Melphalan $8 eng 801 -0
$a US $b DNLM $c 19990101 801 -2
$a SK $b BA006 $c 20020701 980 $x M SYS d005020 LBL 00000nx--j22000003--45-- 005 20240119200949.6 100 $a 19921119csloy0103----ba0 152 $b mesh 250 $a etylmetánsulfonát $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 80(75); was see under METHANESULFONATES 1975-79; ETHYLMESYLATE & MESILATE, ETHYL were see ETHYL METHANESULFONATE 1981-93; ETHYL MESILATE was see ETHYL METHANESULFONATE 1980-93 $8 eng 300 1-
$a Alkanes (1966-1973) $8 eng 300 1-
$a Methane (1966-1973) $8 eng 300 1-
$a Methanesulfonates (1974) $8 eng 300 1-
$a Sulfonic Acids (1966-1973) $8 eng 330 1-
$a An antineoplastic agent with alkylating properties. It also acts as a mutagen by damaging DNA and is used experimentally for that effect. $8 eng 450 $a Ethylmethane Sulfonate $5 e $8 eng 550 $3 sllk_un_auth*d018906 $Y Antineoplastic Agents, Alkylating $5 P $a antineoplastiká alkylačné 550 $3 sllk_un_auth*d009153 $Y Mutagens $5 P $a mutagény 686 $a D02.455.326.146.100.050.500.300 686 $a D02.886.645.600.055.050.510.300 750 $a Ethyl Methanesulfonate $8 eng 801 -0
$a US $b DNLM $c 19921119 801 -2
$a SK $b BA006 $c 20070706 980 $x M SYS d003606 LBL 00000nx--j22000003--45-- 005 20240119200925.3 100 $a 19921111csloy0103----ba0 152 $b mesh 250 $a dakarbazín $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 80(75) $8 eng 300 1-
$a Amides (1966-1974) $8 eng 300 1-
$a Azo Compounds (1966-1972) $8 eng 300 1-
$a Imidazoles (1966-1974) $8 eng 300 1-
$a Triazenes (1972-1974) $8 eng 330 1-
$a An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564) $8 eng 450 $a DTIC $5 e $8 eng 550 $3 sllk_un_auth*d018906 $Y Antineoplastic Agents, Alkylating $5 P $a antineoplastiká alkylačné 686 $a D02.925.200 686 $a D03.383.129.308.240 750 $a Dacarbazine $8 eng 801 -0
$a US $b DNLM $c 19921111 801 -2
$a SK $b BA006 $c 20070706 980 $x M