Number of the records: 1

angiotenzinogén

Subject h.	angiotenzinogén
Subject h.	Angiotensinogen
Entry terms	hypertenzinogén proangiotenzín substrát renínu substrát renínový serpín A8 tetradekapeptid substrátu renínu tetradekapeptid renínového substrátu SERPINA8
English X references	Hypertensinogen Renin-Substrate SERPINA8
Scope note in English	An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver in response to lowered blood pressure and secreted into blood circulation. Angiotensinogen is the inactive precursor of the ANGIOTENSINS produced in the body by successive enzyme cleavages. Cleavage of angiotensinogen by RENIN yields the decapeptide ANGIOTENSIN I. Further cleavage of angiotensin I (by ANGIOTENSIN CONVERTING ENZYME) yields the potent vasoconstrictor octapeptide ANGIOTENSIN II; and then, via other enzymes, other angiotensins also involved in the hemodynamic-regulating RENIN-ANGIOTENSIN SYSTEM.
Pharmacology effect	inhibítory serínových proteináz
Pharmacology effect	Serine Proteinase Inhibitors
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subject heading

Number of the records: 1