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receptory pre enterotoxíny

  1. Subject h.receptory pre enterotoxíny
    Subject h.Receptors, Enterotoxin
    Entry termsreceptor enterotoxínový
    receptory pre guanylín-uroguanylín
    receptory GC-C
    guanylyl cykláza C
    receptor pre guanylyl cyklázu
    receptor pre guanylátcyklázu
    receptor enterotoxínový, tepelne stabilný
    Scope note in EnglishGuanylate cyclase-coupled receptors that bind bacterial ENTEROTOXINS, as well as the endogenous peptides guanylin and uroguanylin. Ligand binding stimulates production of CYCLIC GMP by EPITHELIAL CELLS of the intestinal lumen, altering barrier permeability and mucus secretion. Mutations in the gene (GUCY2C) encoding this receptor are associated with some cases of hereditary diarrhea (Diarrhea 6) and MECONIUM ILEUS.
    Links (1) - MeSH descriptor
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Number of the records: 1  

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