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rodina aldo-ketoreduktáz 1, člen C2

  1. Subject h.rodina aldo-ketoreduktáz 1, člen C2
    Subject h.Aldo-Keto Reductase Family 1 Member C2
    Entry termsAKR1C2 proteín
    dihydrodioldehydrogenáza 2
    dihydrodioldehydrogenáza - proteín viažuci žlčové kyseliny
    Scope note in EnglishAldo-keto reductase that functions with 5-alpha and 5-beta-steroid reductases to convert steroid hormones into the 3-alpha or 5-alpha and 3-alpha or 5-beta-tetrahydrosteroid, including 5-ALPHA-DIHYDROTESTOSTERONE to ANDROSTANE-3,17-DIOL. It also binds to BILE ACIDS. Mutations in the AKR1C2 gene are associated with Type 8 DISORDER OF SEX DEVELOPMENT, 46,XY (SRXY8).
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