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oxaliplatina

Subject h.	oxaliplatina
Subject h.	Oxaliplatin
Entry terms	platinum(2+) etándioát (1R,2R)-1,2-cyklohexánediamín (1:1:1) 1,2-diamíncyklohexán(trans-1)oxolátplatina(II) oxalát 1,2-diaminocyklohexán platiny 1,2-diamíncyclohexán(trans-1)oxalátoplatina(II) cis-oxaláto-(trans-l)-1,2-diamíncyklohexán-platinum(II) eloxatín L-OHP Cpd oxaláto-(1,2-cyklohexándiamín)platinum II platinum(II)-1,2-cyklohexánediamín oxalát oxaliplatina, (SP-4-2-(1R-trans))-izomér oxaliplatina, (SP-4-2-(1S-trans))-izomér oxaliplatina, (SP-4-3-(cis))-izomér platina(2+) etándioát (1R,2R)-1,2-cyklohexándiamín (1:1:1)
English X references	Platinum(2+) ethanedioate (1R,2R)-1,2-cyclohexanediamine (1:1:1)
Scope note in English	An organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane, and with an oxalate ligand which is displaced to yield active oxaliplatin derivatives. These derivatives form inter- and intra-strand DNA crosslinks that inhibit DNA replication and transcription. Oxaliplatin is an antineoplastic agent that is often administered with FLUOROURACIL and FOLINIC ACID in the treatment of metastatic COLORECTAL NEOPLASMS.
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