Progressive deterioration of T-cell function due to chronic antigen stimulation and inflammatory signals, e.g., CHRONIC INFECTION and CANCER. T-cell exhaustion is characterized by weakened immune system, e.g., dysfunctional MEMORY T CELLS differentiation and EPIGENETIC REPRESSION of IMMUNOLOGIC MEMORY effector functions.
See also reference (FX) in Slovak
deplécia lymfocytov senescencia T-buniek
See also reference (FX) in English
Lymphocyte Depletion T-Cell Senescence
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