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cytotoxicita závislá od protilátky sprostredkovaná bunkami

  1. Subject h.cytotoxicita závislá od protilátky sprostredkovaná bunkami
    Subject h.Antibody-Dependent Cell Cytotoxicity
    Entry termsADCC
    cytotoxickosť bunková závislá od protilátky
    cytotoxicita bunková závislá od protilátky
    English X referencesADCC
    Cytotoxicity, Antibody-Dependent Cell
    Scope note in EnglishThe phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a "killer" cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.
    Links (10) - ARTICLES
    (2) - CiBaMed
    (4) - BOOKS
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