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asialoglykoproteíny

  1. Subject h.asialoglykoproteíny
    Subject h.Asialoglycoproteins
    Entry termsasialoglykoproteín
    glykoproteíny desialylované
    English X referencesAsialoglycoprotein
    Scope note in EnglishEndogenous glycoproteins from which SIALIC ACID has been removed by the action of sialidases. They bind tightly to the ASIALOGLYCOPROTEIN RECEPTOR which is located on hepatocyte plasma membranes. After internalization by adsorptive ENDOCYTOSIS they are delivered to LYSOSOMES for degradation. Therefore receptor-mediated clearance of asialoglycoproteins is an important aspect of the turnover of plasma glycoproteins. They are elevated in serum of patients with HEPATIC CIRRHOSIS or HEPATITIS.
    See also reference (FX) in Slovak receptor asialoglykoproteínový
    See also reference (FX) in English Asialoglycoprotein Receptor
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