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toxín cholerový

  1. Subject h.toxín cholerový
    Subject h.Cholera Toxin
    Entry termstoxín cholery
    cholera toxín
    enterotoxín cholery CT
    exotoxín cholery
    cholera exotoxín
    toxín cholery, podjednotka A
    toxín cholery, subjednotka A
    toxín cholery, podjednotka B
    toxín cholery, subjednotka B
    toxín cholery A
    cholera toxín A
    toxín cholery B
    cholera toxín B
    protomér A toxínu cholery
    protomér A cholerového toxínu
    protomér B toxínu cholery
    protomér B cholerového toxínu
    choleragén
    choleragenoid
    procholeragenoid
    English X referencesCholera Toxin A
    Cholera Toxin B
    Cholera Toxin Protomer A
    Cholera Toxin Protomer B
    Cholera Toxin Subunit A
    Cholera Toxin Subunit B
    Choleragen
    Choleragenoid
    Scope note in EnglishAn ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit and the B protomer which consists of 5 light (L) or B subunits. The catalytic A subunit is proteolytically cleaved into fragments A1 and A2. The A1 fragment is a MONO(ADP-RIBOSE) TRANSFERASE. The B protomer binds cholera toxin to intestinal epithelial cells and facilitates the uptake of the A1 fragment. The A1 catalyzed transfer of ADP-RIBOSE to the alpha subunits of heterotrimeric G PROTEINS activates the production of CYCLIC AMP. Increased levels of cyclic AMP are thought to modulate release of fluid and electrolytes from intestinal crypt cells.
    Pharmacology effect adjuvanciá imunologické
    jedy
    Pharmacology effect Adjuvants, Immunologic
    Poisons
    Links (1) - ARTICLES
    (1) - MeSH descriptor
    (1) - CiBaMed
    (3) - BOOKS
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Number of the records: 1  

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