An ADP-ribosylating polypeptide produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains MONO(ADP-RIBOSE) TRANSFERASES which transfers ADP RIBOSE to PEPTIDE ELONGATION FACTOR 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.
Pharmacology effect
jedy
Pharmacology effect
Poisons
See also reference (FX) in Slovak
toxoid difterický
See also reference (FX) in English
Diphtheria Toxoid
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(2) - ARTICLES
(2) - MeSH descriptor
(1) - CiBaMed
(1) - BOOKS
subject heading
Number of the records: 1
openseadragon
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