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prióny

  1. Subject h.prióny
    Subject h.Prions
    Entry termsprión
    vírus encefalopatie noriek
    English X referencesMink Encephalopathy Virus
    Prion
    Scope note in EnglishSmall proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.
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    (1) - MeSH descriptor
    (16) - CiBaMed
    (10) - BOOKS
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Number of the records: 1  

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