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steroid-12-alfa-hydroxyláza

  1. Subject h.steroid-12-alfa-hydroxyláza
    Subject h.Steroid 12-alpha-Hydroxylase
    Entry termssteroid-12-monooxygenáza
    sterol-12-alfa-hydroxyláza
    12-alfa-hydroxyláza
    English X references12-alpha-Hydroxylase
    Steroid 12-Monooxygenase
    Sterol 12-alpha-Hydroxylase
    Scope note in EnglishA liver microsomal cytochrome P450 enzyme that catalyzes the 12-alpha-hydroxylation of a broad spectrum of sterols in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP8B1gene, converts 7-alpha-hydroxy-4-cholesten-3-one to 7-alpha-12-alpha-dihydroxy-4-cholesten-3-one and is required in the synthesis of BILE ACIDS from cholesterol.
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Number of the records: 1  

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