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Fallotova trilógia

  1. MeSH Tree Structures - Fallotova trilógia


    [c14.240.400.960]

    [c14.280.400.960]

    [c16.131.240.400.960]

    Scope note in EnglishProtein synthesized by CLOSTRIDIUM TETANI as a single chain of ~150 kDa with 35% sequence identity to BOTULINUM TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. Tetanolysin is the hemolytic and tetanospasmin is the neurotoxic principle. The toxin causes disruption of the inhibitory mechanisms of the CNS, thus permitting uncontrolled nervous activity, leading to fatal CONVULSIONS.
    Pharmacology effect neurotoxíny
    Pharmacology effect Neurotoxins
    See also reference (FX) in Slovak antitoxín tetanický
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Number of the records: 1  

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