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lupus antikoagulans

  1. Subject h.lupus antikoagulans
    Subject h.Lupus Coagulation Inhibitor
    Entry termsinhibítor koagulácie, lupusový
    antikoagulant lupusový
    autoprotilátky lupusové antikoagulačné
    autoprotilátka antikoagulačná lupusová
    English X referencesLupus Anticoagulant
    Lupus Anticoagulant Autoantibodies
    Lupus Anticoagulant Autoantibody
    Scope note in EnglishAn antiphospholipid antibody found in association with a variety of diseases (e.g., SYSTEMIC LUPUS ERYTHEMATOSUS and ANTIPHOSPHOLIPID SYNDROME) as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.
    Pharmacology effect faktory imunologické
    Pharmacology effect Immunologic Factors
    See also reference (FX) in Slovak syndróm antifosfolipidový
    See also reference (FX) in English Antiphospholipid Syndrome
    Links (10) - ARTICLES
    (2) - MeSH descriptor
    (2) - CiBaMed
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Number of the records: 1  

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