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myši inbredné mdx

  1. Subject h.myši inbredné mdx
    Subject h.Mice, Inbred mdx
    Entry termsmyši inbrídované mdx
    Scope note in EnglishA strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.
    See also reference (FX) in Slovak dystrofie svalové
    See also reference (FX) in English Muscular Dystrophies
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Number of the records: 1  

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