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ATP-viažuci kazetový transportér, podrodina B

  1. Subject h.ATP-viažuci kazetový transportér, podrodina B
    Subject h.ATP Binding Cassette Transporter, Subfamily B
    Entry termsP-glykoproteíny
    proteíny mnoholiekovej rezistencie
    proteíny mnohopočetnej liekovej rezistencie
    proteíny MDR
    ATP-viažuci kazetový transportér, podrodina B
    kazeta viažuca ATP, subrodina proteínov B
    kazeta viažuca ATP, podrodina proteínov B
    ATP-viažuce kazetové proteíny, podrodina B
    English X referencesMultidrug Resistance Proteins
    P-Glycoproteins
    Scope note in EnglishA subfamily of transmembrane proteins from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS that are closely related in sequence to ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1. When overexpressed, they function as ATP-dependent efflux pumps able to extrude lipophilic drugs (especially ANTINEOPLASTIC AGENTS) from cells, causing multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
    See also reference (FX) in Slovak rezistencia lieková mnohopočetná
    gény MDR
    proteíny spojené s mnohopočetnou liekovou rezistenciou
    rodamín 123
    See also reference (FX) in English Drug Resistance, Multiple
    Genes, MDR
    Multidrug Resistance-Associated Proteins
    Rhodamine 123
    Links (17) - ARTICLES
    (4) - MeSH descriptor
    (2) - CiBaMed
    (2) - BOOKS
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Number of the records: 1  

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