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cytochróm P-450 CYP2B1

  1. Subject h.cytochróm P-450 CYP2B1
    Subject h.Cytochrome P-450 CYP2B1
    Entry termsBROD
    PROD
    CYP 2B1
    CYP2B1
    cytochróm P450 2B1
    benzyloxyrezorufín O-dealkyláza
    pentoxyrezorufín O-dealkyláza
    7-pentylrezorufín O-depentyláza
    7-benzyloxyrezorufín O-dealkyláza
    English X referencesBROD
    Benzyloxyresorufin O-Dealkylase
    CYP2B1
    PROD
    Pentoxyresorufin O-Dealkylase
    Scope note in EnglishA major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.
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