A family of polypeptides purified from snake venoms, which contain the arginine-glycine-aspartic acid (RGD) sequence. The RGD tripeptide binds to integrin receptors and thus competitively inhibits normal integrin-ligand interactions. Disintegrins thus block adhesive functions and act as platelet aggregation inhibitors.
Pharmacology effect
inhibítory agregácie trombocytov
Pharmacology effect
Platelet Aggregation Inhibitors
subject heading
openseadragon
Number of the records: 1
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